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For example, if a patient presents with elevated GH and IGF-I, it is important to rule out underlying impairment in renal function as elevated serum GH and IGF-I levels may also be present in patients with CKD, and not diagnose the patient as having acromegaly

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[DOI] [PubMed] [Google Scholar] [91].Yamaguchi T, Nagao S, Wallace DP, Belibi FA, Cowley BD, Pelling JC, Grantham JJ, Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys, Kidney International, 63 (2003) 1983–1994

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